The Mould that Changed the World is an internationally-touring sell-out musical about antimicrobial resistance (AMR).

It tells the story of Alexander Fleming’s famous discovery of penicillin in 1928, charting the rise and fall of antibiotics. We travel into the reality of life without these precious drugs, and the approaching era of superbugs and death from common infections that we can no longer treat, using theatre to engage the general public in this urgent global health threat.

The musical sold out runs at the Edinburgh Festival Fringe in 2018 and 2022, and showing at Webster’s Theatre in Glasgow and the Ovalhouse in London, before touring the East coast of the USA in late 2022. It has also been showcased in Barbados for the Prime Minister Mia Mottley at the high-level AMR leaders group meeting in 2023, as well as at the Houses of Parliament for MPs in collaboration with WaterAid and the British Society for Antimicrobial Chemotherapy in support of the publication of a paper on the need for clean water in lower and middle income countries to prevent the spread of AMR.

Uniquely, the musical combines a touring professional West End cast of actors with a chorus of scientists and healthcare professionals local to each city we perform in. This allows us not only to connect with local people and communities but also to give voice to and perform alongside people who understand the issue of AMR and work with it in their everyday lives. To hear some of their stories, visit Chorus Insights.

The musical also has a Schools Version which can be performed by 9-11 year olds with the help of an online video resource, teaching children how to perform the songs and scenes from the musical. For more information, visit Resources.